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High-Throughput Method for the Simultaneous Determination of Doxorubicin Metabolites in Rat Urine after Treatment with Different Drug Nanoformulations

Doxorubicin (DOX) is one of the most effective cytotoxic agents against malignant diseases. However, the clinical application of DOX is limited, due to dose-related toxicity. The development of DOX nanoformulations that significantly reduce its toxicity and affect the metabolic pathway of the drug r...

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Detalles Bibliográficos
Autores principales: Zorić, Lara, Drinković, Nikša, Micek, Vedran, Frkanec, Leo, Türeli, Akif Emre, Günday-Türeli, Nazende, Vinković Vrček, Ivana, Frkanec, Ruža
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8877250/
https://www.ncbi.nlm.nih.gov/pubmed/35208967
http://dx.doi.org/10.3390/molecules27041177