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High-Throughput Method for the Simultaneous Determination of Doxorubicin Metabolites in Rat Urine after Treatment with Different Drug Nanoformulations
Doxorubicin (DOX) is one of the most effective cytotoxic agents against malignant diseases. However, the clinical application of DOX is limited, due to dose-related toxicity. The development of DOX nanoformulations that significantly reduce its toxicity and affect the metabolic pathway of the drug r...
Autores principales: | Zorić, Lara, Drinković, Nikša, Micek, Vedran, Frkanec, Leo, Türeli, Akif Emre, Günday-Türeli, Nazende, Vinković Vrček, Ivana, Frkanec, Ruža |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8877250/ https://www.ncbi.nlm.nih.gov/pubmed/35208967 http://dx.doi.org/10.3390/molecules27041177 |
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