Design and Synthesis of Arylpiperazine Serotonergic/Dopaminergic Ligands with Neuroprotective Properties

Long-chain arylpiperazine scaffold is a versatile template to design central nervous system (CNS) drugs that target serotonin and dopamine receptors. Here we describe the synthesis and biological evaluation of ten new arylpiperazine derivatives designed to obtain an affinity profile at serotonin 5-H...

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Detalles Bibliográficos
Autores principales: Mastromarino, Margherita, Niso, Mauro, Abate, Carmen, Proschak, Ewgenij, Dubiel, Mariam, Stark, Holger, Castro, Marián, Lacivita, Enza, Leopoldo, Marcello
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8877291/
https://www.ncbi.nlm.nih.gov/pubmed/35209087
http://dx.doi.org/10.3390/molecules27041297

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8877291/
https://www.ncbi.nlm.nih.gov/pubmed/35209087
http://dx.doi.org/10.3390/molecules27041297

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