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Minor Impact of A258D Mutation on Biochemical and Enzymatic Properties of Leishmania infantum GDP-Mannose Pyrophosphorylase

Background: Leishmaniasis, a vector-borne disease caused by the protozoan parasite from the genus Leishmania, is endemic to tropical and subtropical areas. Few treatments are available against leishmaniasis, with all presenting issues of toxicity, resistance, and/or cost. In this context, the develo...

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Detalles Bibliográficos
Autores principales: Mao, Wei, Lazar, Noureddine, van Tilbeurgh, Herman, Loiseau, Philippe M., Pomel, Sébastien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8877407/
https://www.ncbi.nlm.nih.gov/pubmed/35208687
http://dx.doi.org/10.3390/microorganisms10020231