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Minor Impact of A258D Mutation on Biochemical and Enzymatic Properties of Leishmania infantum GDP-Mannose Pyrophosphorylase
Background: Leishmaniasis, a vector-borne disease caused by the protozoan parasite from the genus Leishmania, is endemic to tropical and subtropical areas. Few treatments are available against leishmaniasis, with all presenting issues of toxicity, resistance, and/or cost. In this context, the develo...
Autores principales: | Mao, Wei, Lazar, Noureddine, van Tilbeurgh, Herman, Loiseau, Philippe M., Pomel, Sébastien |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8877407/ https://www.ncbi.nlm.nih.gov/pubmed/35208687 http://dx.doi.org/10.3390/microorganisms10020231 |
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