In Vitro and In Vivo Pharmacological Characterization of a Novel TRPM8 Inhibitor Chemotype Identified by Small-Scale Preclinical Screening

Transient receptor potential melastatin type 8 (TRPM8) is a target for the treatment of different physio-pathological processes. While TRPM8 antagonists are reported as potential drugs for pain, cancer, and inflammation, to date only a limited number of chemotypes have been investigated and thus a l...

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Detalles Bibliográficos
Autores principales: Iraci, Nunzio, Ostacolo, Carmine, Medina-Peris, Alicia, Ciaglia, Tania, Novoselov, Anton M., Altieri, Andrea, Cabañero, David, Fernandez-Carvajal, Asia, Campiglia, Pietro, Gomez-Monterrey, Isabel, Bertamino, Alessia, Kurkin, Alexander V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8877448/
https://www.ncbi.nlm.nih.gov/pubmed/35216186
http://dx.doi.org/10.3390/ijms23042070

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8877448/
https://www.ncbi.nlm.nih.gov/pubmed/35216186
http://dx.doi.org/10.3390/ijms23042070

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