Cooperative Chikungunya Virus Membrane Fusion and Its Substoichiometric Inhibition by CHK-152 Antibody

Chikungunya virus (CHIKV) presents a major burden on healthcare systems worldwide, but specific treatment remains unavailable. Attachment and fusion of CHIKV to the host cell membrane is mediated by the E1/E2 protein spikes. We used an in vitro single-particle fusion assay to study the effect of the...

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Detalles Bibliográficos
Autores principales: Blijleven, Jelle S., Bouma, Ellen M., van Duijl-Richter, Mareike K. S., Smit, Jolanda M., van Oijen, Antoine M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8877538/
https://www.ncbi.nlm.nih.gov/pubmed/35215863
http://dx.doi.org/10.3390/v14020270

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8877538/
https://www.ncbi.nlm.nih.gov/pubmed/35215863
http://dx.doi.org/10.3390/v14020270

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