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Hypoxia-Inducible Factor-2 Alpha Regulates the Migration of Fibroblast-like Synoviocytes via Oxidative Stress-Induced CD70 Expression in Patients with Rheumatoid Arthritis

This study aimed to examine the role of CD70, which is highly expressed on fibroblast-like synoviocytes (FLS), in rheumatoid arthritis (RA) patients. FLS isolated from RA (n = 14) and osteoarthritis (OA, n = 4) patients were stimulated with recombinant interleukin-17 (IL-17; 5 ng/mL) and tumor necro...

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Detalles Bibliográficos
Autores principales: Yoo, Su-Jin, Lee, Ha-Reum, Kim, Jinhyun, Yoo, In Seol, Park, Chan Keol, Kang, Seong Wook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8877612/
https://www.ncbi.nlm.nih.gov/pubmed/35216458
http://dx.doi.org/10.3390/ijms23042342