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Investigation of the Antiremodeling Effects of Losartan, Mirabegron and Their Combination on the Development of Doxorubicin-Induced Chronic Cardiotoxicity in a Rat Model

Despite the effectiveness of doxorubicin (DOXO) as a chemotherapeutic agent, dose-dependent development of chronic cardiotoxicity limits its application. The angiotensin-II receptor blocker losartan is commonly used to treat cardiac remodeling of various etiologies. The beta-3 adrenergic receptor ag...

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Detalles Bibliográficos
Autores principales: Freiwan, Marah, Kovács, Mónika G., Kovács, Zsuzsanna Z. A., Szűcs, Gergő, Dinh, Hoa, Losonczi, Réka, Siska, Andrea, Kriston, András, Kovács, Ferenc, Horváth, Péter, Földesi, Imre, Cserni, Gábor, Dux, László, Csont, Tamás, Sárközy, Márta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8877618/
https://www.ncbi.nlm.nih.gov/pubmed/35216317
http://dx.doi.org/10.3390/ijms23042201