Hydrogen-Deuterium Exchange Mass Spectrometry Reveals a Novel Binding Region of a Neutralizing Fully Human Monoclonal Antibody to Anthrax Protective Antigen

Anthrax vaccine adsorbed (AVA) containing protective antigen (PA) is the only FDA-approved anthrax vaccine in the United States. Characterization of the binding of AVA-induced anti-PA human antibodies against the PA antigen after vaccination is crucial to understanding mechanisms of the AVA-elicited...

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Detalles Bibliográficos
Autores principales: Fang, Mulin, Wang, Zhe, Norris, Kathleen, James, Judith A., Wu, Si, Smith, Kenneth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8877668/
https://www.ncbi.nlm.nih.gov/pubmed/35202120
http://dx.doi.org/10.3390/toxins14020092

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8877668/
https://www.ncbi.nlm.nih.gov/pubmed/35202120
http://dx.doi.org/10.3390/toxins14020092

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