Allosteric Determinants of the SARS-CoV-2 Spike Protein Binding with Nanobodies: Examining Mechanisms of Mutational Escape and Sensitivity of the Omicron Variant

Structural and biochemical studies have recently revealed a range of rationally engineered nanobodies with efficient neutralizing capacity against the SARS-CoV-2 virus and resilience against mutational escape. In this study, we performed a comprehensive computational analysis of the SARS-CoV-2 spike...

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Detalles Bibliográficos
Autor principal: Verkhivker, Gennady
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8877688/
https://www.ncbi.nlm.nih.gov/pubmed/35216287
http://dx.doi.org/10.3390/ijms23042172

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8877688/
https://www.ncbi.nlm.nih.gov/pubmed/35216287
http://dx.doi.org/10.3390/ijms23042172

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