Aggregatibacter actinomycetemcomitans Leukotoxin Activates the NLRP3 Inflammasome and Cell-to-Cell Communication

Carriers of highly leukotoxic genotypes of Aggregatibacter actinomycetemcomitans are at high risk for rapid degradation of tooth-supporting tissues. The leukotoxin (LtxA) expressed by this bacterium induces a rapid pro-inflammatory response in leukocytes that results in cell death. The aim of the pr...

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Detalles Bibliográficos
Autores principales: Kelk, Peyman, Moghbel, Nick Sina, Hirschfeld, Josefine, Johansson, Anders
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8877716/
https://www.ncbi.nlm.nih.gov/pubmed/35215102
http://dx.doi.org/10.3390/pathogens11020159

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8877716/
https://www.ncbi.nlm.nih.gov/pubmed/35215102
http://dx.doi.org/10.3390/pathogens11020159

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