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Synergistic Adverse Effects of Azithromycin and Hydroxychloroquine on Human Cardiomyocytes at a Clinically Relevant Treatment Duration

Adverse effects of drug combinations and their underlying mechanisms are highly relevant for safety evaluation, but often not fully studied. Hydroxychloroquine (HCQ) and azithromycin (AZM) were used as a combination therapy in the treatment of COVID-19 patients at the beginning of the pandemic, lead...

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Detalles Bibliográficos
Autores principales: Li, Wener, Luo, Xiaojing, Poetsch, Mareike S., Oertel, Reinhard, Nichani, Kapil, Schneider, Martin, Strano, Anna, Hasse, Marcel, Steiner, Robert-Patrick, Cyganek, Lukas, Hettwer, Karina, Uhlig, Steffen, Simon, Kirsten, Guan, Kaomei, Schubert, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8877825/
https://www.ncbi.nlm.nih.gov/pubmed/35215332
http://dx.doi.org/10.3390/ph15020220