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Identification and Validation of Ikaros (IKZF1) as a Cancer Driver Gene for Marek’s Disease Virus-Induced Lymphomas

Marek’s disease virus (MDV) is the causative agent for Marek’s disease (MD), which is characterized by T-cell lymphomas in chickens. While the viral Meq oncogene is necessary for transformation, it is insufficient, as not every bird infected with virulent MDV goes on to develop a gross tumor. Thus,...

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Detalles Bibliográficos
Autores principales: Steep, Alec, Hildebrandt, Evin, Xu, Hongen, Hearn, Cari, Frishman, Dmitrij, Niikura, Masahiro, Dunn, John R., Kim, Taejoong, Conrad, Steven J., Muir, William M., Cheng, Hans H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8877892/
https://www.ncbi.nlm.nih.gov/pubmed/35208856
http://dx.doi.org/10.3390/microorganisms10020401