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Novel Cocrystals of Vonoprazan: Machine Learning-Assisted Discovery

Vonoprazan (VPZ) is the first-in-class potassium-competitive acid blocker (P-CAB), and has many advantages over proton pump inhibitors (PPIs). It is administered as a fumarate salt for the treatment of acid-related diseases, including reflux esophagitis, gastric ulcer, and duodenal ulcer, and for er...

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Detalles Bibliográficos
Autores principales: Lee, Min-Jeong, Kim, Ji-Yoon, Kim, Paul, Lee, In-Seo, Mswahili, Medard E., Jeong, Young-Seob, Choi, Guang J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8877905/
https://www.ncbi.nlm.nih.gov/pubmed/35214161
http://dx.doi.org/10.3390/pharmaceutics14020429