A New Calcium(II)-Based Substitute for Enrofloxacin with Improved Medicinal Potential

Enrofloxacin (EFX) reacting with Ca(II) afforded a new complex, [Ca(EFX)(2)(H(2)O)(4)] (EFX-Ca), which was structurally characterized both in solid and solution chemistry. E. coli and S. typhi were tested to be the most sensitive strains for EFX-Ca. The LD(50) value of EFX-Ca in mice was 7736 mg/kg,...

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Detalles Bibliográficos
Autores principales: Yan, Hou-Tian, Liu, Rui-Xue, Yang, Qi-Zhen, Liu, Yan-Cheng, Li, Hong-Chang, Guo, Rui-Feng, Wu, Lin-Hua, Liu, Li-Min, Liang, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8878047/
https://www.ncbi.nlm.nih.gov/pubmed/35213984
http://dx.doi.org/10.3390/pharmaceutics14020249

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8878047/
https://www.ncbi.nlm.nih.gov/pubmed/35213984
http://dx.doi.org/10.3390/pharmaceutics14020249

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