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Relationships between Inhibition, Transport and Enhanced Transport via the Organic Cation Transporter 1

The organic cation transporter 1 (OCT1, SLC22A1) transports a large number of structurally diverse endogenous and exogenous substrates. There are numerous known competitive and non-competitive inhibitors of OCT1, but there are no studies systematically analyzing the relationship between transport, s...

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Detalles Bibliográficos
Autores principales: Jensen, Ole, Gebauer, Lukas, Brockmöller, Jürgen, Dücker, Christof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8878159/
https://www.ncbi.nlm.nih.gov/pubmed/35216120
http://dx.doi.org/10.3390/ijms23042007