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Interdisciplinary Study of the Effects of Dipeptidyl-Peptidase III Cancer Mutations on the KEAP1-NRF2 Signaling Pathway

Dipeptidyl peptidase III (DPP III) is associated with cancer progression via interaction with KEAP1, leading to upregulation of the KEAP1-NRF2 oxidative stress pathway. Numerous DPP III mutations have been found in human tumor genomes, and it is suggested that some of them may alter affinity for KEA...

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Detalles Bibliográficos
Autores principales: Matić, Sara, Tomašić Paić, Ana, Sobočanec, Sandra, Pinterić, Marija, Pipalović, Goran, Martinčić, Monika, Matovina, Mihaela, Tomić, Sanja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8878202/
https://www.ncbi.nlm.nih.gov/pubmed/35216111
http://dx.doi.org/10.3390/ijms23041994