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Prediction of Drug Targets for Specific Diseases Leveraging Gene Perturbation Data: A Machine Learning Approach

Identification of the correct targets is a key element for successful drug development. However, there are limited approaches for predicting drug targets for specific diseases using omics data, and few have leveraged expression profiles from gene perturbations. We present a novel computational appro...

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Detalles Bibliográficos
Autores principales: Zhao, Kai, Shi, Yujia, So, Hon-Cheong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8878225/
https://www.ncbi.nlm.nih.gov/pubmed/35213968
http://dx.doi.org/10.3390/pharmaceutics14020234