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Tissue Inhibitor of Metalloproteases 3 (TIMP-3): In Vivo Analysis Underpins Its Role as a Master Regulator of Ectodomain Shedding

The proteolytical cleavage of transmembrane proteins with subsequent release of their extracellular domain, so-called ectodomain shedding, is a post-translational modification that plays an essential role in several biological processes, such as cell communication, adhesion and migration. Metallopro...

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Detalles Bibliográficos
Autores principales: Spanò, Donatella Pia, Scilabra, Simone Dario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8878240/
https://www.ncbi.nlm.nih.gov/pubmed/35207132
http://dx.doi.org/10.3390/membranes12020211