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Sheltered in Stromal Tissue Cells, Trypanosoma cruzi Orchestrates Inflammatory Neovascularization via Activation of the Mast Cell Chymase Pathway

Microangiopathy may worsen the clinical outcome of Chagas disease. Given the obstacles to investigating the dynamics of inflammation and angiogenesis in heart tissues parasitized by Trypanosoma cruzi, here we used intravital microscopy (IVM) to investigate microcirculatory alterations in the hamster...

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Detalles Bibliográficos
Autores principales: Vellasco, Lucas, Svensjö, Erik, Bulant, Carlos Alberto, Blanco, Pablo Javier, Nogueira, Fábio, Domont, Gilberto, de Almeida, Natália Pinto, Nascimento, Clarissa Rodrigues, Silva-dos-Santos, Danielle, Carvalho-Pinto, Carla Eponina, Medei, Emiliano Horácio, Almeida, Igor C., Scharfstein, Julio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8878313/
https://www.ncbi.nlm.nih.gov/pubmed/35215131
http://dx.doi.org/10.3390/pathogens11020187