Evaluation of New Antimicrobial Agents Based on tris(1H-Indol-3-yl)methylium Salts: Activity, Toxicity, Suppression of Experimental Sepsis in Mice

The antimicrobial activity and toxicity of three novel synthetic antibacterial agents containing tris(1H-indol-3-yl)methylium fragment were studied in vitro and in vivo. All compounds in vitro revealed high activity (minimal inhibitory concentration (MIC) 0.13–1.0 µg/mL) against bacteria that were e...

Descripción completa

Detalles Bibliográficos
Autores principales: Trenin, Alexey S., Isakova, Elena B., Treshchalin, Michael I., Polozkova, Vasilisa A., Mirchink, Elena P., Panov, Alexey A., Simonov, Alexander Y., Bychkova, Olga P., Tatarskiy, Victor V., Lavrenov, Sergey N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8878324/
https://www.ncbi.nlm.nih.gov/pubmed/35215231
http://dx.doi.org/10.3390/ph15020118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8878324/
https://www.ncbi.nlm.nih.gov/pubmed/35215231
http://dx.doi.org/10.3390/ph15020118

Ejemplares similares