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Evaluation of New Antimicrobial Agents Based on tris(1H-Indol-3-yl)methylium Salts: Activity, Toxicity, Suppression of Experimental Sepsis in Mice
The antimicrobial activity and toxicity of three novel synthetic antibacterial agents containing tris(1H-indol-3-yl)methylium fragment were studied in vitro and in vivo. All compounds in vitro revealed high activity (minimal inhibitory concentration (MIC) 0.13–1.0 µg/mL) against bacteria that were e...
Autores principales: | Trenin, Alexey S., Isakova, Elena B., Treshchalin, Michael I., Polozkova, Vasilisa A., Mirchink, Elena P., Panov, Alexey A., Simonov, Alexander Y., Bychkova, Olga P., Tatarskiy, Victor V., Lavrenov, Sergey N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8878324/ https://www.ncbi.nlm.nih.gov/pubmed/35215231 http://dx.doi.org/10.3390/ph15020118 |
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