Risedronate and Methotrexate Are High-Affinity Inhibitors of New Delhi Metallo-β-Lactamase-1 (NDM-1): A Drug Repurposing Approach

Bacteria expressing New Delhi metallo-β-lactamase-1 (NDM-1) can hydrolyze β-lactam antibiotics (penicillins, cephalosporins, and carbapenems) and, thus, mediate multidrug resistance. The worldwide dissemination of NDM-1 poses a serious threat to public health, imposing a huge economic burden in the...

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Detalles Bibliográficos
Autores principales: Muteeb, Ghazala, Alsultan, Abdulrahman, Farhan, Mohd, Aatif, Mohammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8878330/
https://www.ncbi.nlm.nih.gov/pubmed/35209073
http://dx.doi.org/10.3390/molecules27041283

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8878330/
https://www.ncbi.nlm.nih.gov/pubmed/35209073
http://dx.doi.org/10.3390/molecules27041283

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