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Risedronate and Methotrexate Are High-Affinity Inhibitors of New Delhi Metallo-β-Lactamase-1 (NDM-1): A Drug Repurposing Approach

Bacteria expressing New Delhi metallo-β-lactamase-1 (NDM-1) can hydrolyze β-lactam antibiotics (penicillins, cephalosporins, and carbapenems) and, thus, mediate multidrug resistance. The worldwide dissemination of NDM-1 poses a serious threat to public health, imposing a huge economic burden in the...

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Detalles Bibliográficos
Autores principales:	Muteeb, Ghazala, Alsultan, Abdulrahman, Farhan, Mohd, Aatif, Mohammad
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8878330/ https://www.ncbi.nlm.nih.gov/pubmed/35209073 http://dx.doi.org/10.3390/molecules27041283

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