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Adaptation of the Kirkstall QV600 LLI Microfluidics System for the Study of Gastrointestinal Absorption by Mass Spectrometry Imaging and LC-MS/MS

Absorption studies on oral drugs can be difficult due to the challenge of replicating the complex structure and environment of the GI tract. Drug absorption studies can be conducted using in vivo and ex vivo animal tissue or animal-free techniques. These studies typically involve the use of Caco-2 c...

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Detalles Bibliográficos
Autores principales: Spencer, Chloe E., Rumbelow, Stephen, Mellor, Steve, Duckett, Catherine J., Clench, Malcolm R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8878338/
https://www.ncbi.nlm.nih.gov/pubmed/35214096
http://dx.doi.org/10.3390/pharmaceutics14020364