Ferritinophagy and α-Synuclein: Pharmacological Targeting of Autophagy to Restore Iron Regulation in Parkinson’s Disease

A major hallmark of Parkinson’s disease (PD) is the fatal destruction of dopaminergic neurons within the substantia nigra pars compacta. This event is preceded by the formation of Lewy bodies, which are cytoplasmic inclusions composed of α-synuclein protein aggregates. A triad contribution of α-synu...

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Detalles Bibliográficos
Autores principales: Boag, Matthew K., Roberts, Angus, Uversky, Vladimir N., Ma, Linlin, Richardson, Des R., Pountney, Dean L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8878351/
https://www.ncbi.nlm.nih.gov/pubmed/35216492
http://dx.doi.org/10.3390/ijms23042378

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8878351/
https://www.ncbi.nlm.nih.gov/pubmed/35216492
http://dx.doi.org/10.3390/ijms23042378

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