Increased Targeting Area in Tumors by Dual-Ligand Modification of Liposomes with RGD and TAT Peptides

Modification with polyethylene glycol (PEGylation) and the use of rigid phospholipids drastically improve the pharmacokinetics of chemotherapeutics and result in more manageable or reduced side-effects. A major drawback is retarded cellular delivery of content, which, along with tumor heterogeneity,...

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Detalles Bibliográficos
Autores principales: Amin, Mohamadreza, Mansourian, Mercedeh, Burgers, Peter C., Amin, Bahareh, Jaafari, Mahmoud Reza, ten Hagen, Timo L. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8878433/
https://www.ncbi.nlm.nih.gov/pubmed/35214190
http://dx.doi.org/10.3390/pharmaceutics14020458

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8878433/
https://www.ncbi.nlm.nih.gov/pubmed/35214190
http://dx.doi.org/10.3390/pharmaceutics14020458

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