A Novel α4/7-Conotoxin QuIA Selectively Inhibits α3β2 and α6/α3β4 Nicotinic Acetylcholine Receptor Subtypes with High Efficacy

α6β4 nAChR is expressed in the peripheral and central nervous systems and is associated with pain, addiction, and movement disorders. Natural α-conotoxins (α-CTxs) can effectively block different nAChR subtypes with higher efficacy and selectivity. However, the research on α6β4 nAChR is relatively p...

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Detalles Bibliográficos
Autores principales: Wang, Liujun, Wu, Xixi, Zhu, Xiaopeng, Zhangsun, Dongting, Wu, Yong, Luo, Sulan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8878501/
https://www.ncbi.nlm.nih.gov/pubmed/35200675
http://dx.doi.org/10.3390/md20020146

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8878501/
https://www.ncbi.nlm.nih.gov/pubmed/35200675
http://dx.doi.org/10.3390/md20020146

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