From the North Sea to Drug Repurposing, the Antiseizure Activity of Halimide and Plinabulin

PharmaSea performed large-scale in vivo screening of marine natural product (MNP) extracts, using zebrafish embryos and larvae, to identify compounds with the potential to treat epilepsy. In this study, we report the discovery of two new antiseizure compounds, the 2,5-diketopiperazine halimide and i...

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Detalles Bibliográficos
Autores principales: Copmans, Daniëlle, Kildgaard, Sara, Roux, Emma, Partoens, Michèle, Steurs, Gert, Wang, Xinhui, De Borggraeve, Wim M., Esguerra, Camila V., Crawford, Alexander D., Larsen, Thomas O., de Witte, Peter A. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8878679/
https://www.ncbi.nlm.nih.gov/pubmed/35215359
http://dx.doi.org/10.3390/ph15020247

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8878679/
https://www.ncbi.nlm.nih.gov/pubmed/35215359
http://dx.doi.org/10.3390/ph15020247

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