Targeting the TP53/MDM2 axis enhances radiation sensitivity in atypical teratoid rhabdoid tumors

Atypical teratoid rhabdoid tumor (ATRT) is a highly aggressive pediatric brain tumor. Despite radiation, aggressive chemotherapy and autologous stem cell rescue, children usually have a poor survival time. In the present study, the role of TP53/MDM2 interaction in ATRT was investigated. A functional...

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Detalles Bibliográficos
Autores principales: Alimova, Irina, Wang, Dong, Danis, Etienne, Pierce, Angela, Donson, Andrew, Serkova, Natalie, Madhavan, Krishna, Lakshmanachetty, Senthilnath, Balakrishnan, Ilango, Foreman, Nicholas K., Mitra, Siddhartha, Venkataraman, Sujatha, Vibhakar, Rajeev
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8878716/
https://www.ncbi.nlm.nih.gov/pubmed/35179215
http://dx.doi.org/10.3892/ijo.2022.5322

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8878716/
https://www.ncbi.nlm.nih.gov/pubmed/35179215
http://dx.doi.org/10.3892/ijo.2022.5322

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