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Targeting the TP53/MDM2 axis enhances radiation sensitivity in atypical teratoid rhabdoid tumors

Atypical teratoid rhabdoid tumor (ATRT) is a highly aggressive pediatric brain tumor. Despite radiation, aggressive chemotherapy and autologous stem cell rescue, children usually have a poor survival time. In the present study, the role of TP53/MDM2 interaction in ATRT was investigated. A functional...

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Detalles Bibliográficos
Autores principales:	Alimova, Irina, Wang, Dong, Danis, Etienne, Pierce, Angela, Donson, Andrew, Serkova, Natalie, Madhavan, Krishna, Lakshmanachetty, Senthilnath, Balakrishnan, Ilango, Foreman, Nicholas K., Mitra, Siddhartha, Venkataraman, Sujatha, Vibhakar, Rajeev
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2022
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8878716/ https://www.ncbi.nlm.nih.gov/pubmed/35179215 http://dx.doi.org/10.3892/ijo.2022.5322

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