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A Nanosized Codelivery System Based on Intracellular Stimuli-Triggered Dual-Drug Release for Multilevel Chemotherapy Amplification in Drug-Resistant Breast Cancer

Lacking nano-systems for precisely codelivering the chemotherapeutics paclitaxel (PTX) and the natural P-glycoprotein (P-gp) inhibitor, quercetin (QU), into cancer cells and controlling their intracellular release extremely decreased the anticancer effects in multidrug resistant (MDR) tumors. To ove...

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Detalles Bibliográficos
Autores principales: Guo, Yufan, Liu, Shuo, Luo, Fazhen, Tang, Dongyun, Yang, Tianshu, Yang, Xiuru, Xie, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8878749/
https://www.ncbi.nlm.nih.gov/pubmed/35214154
http://dx.doi.org/10.3390/pharmaceutics14020422