Cargando…

A Nanosized Codelivery System Based on Intracellular Stimuli-Triggered Dual-Drug Release for Multilevel Chemotherapy Amplification in Drug-Resistant Breast Cancer

Lacking nano-systems for precisely codelivering the chemotherapeutics paclitaxel (PTX) and the natural P-glycoprotein (P-gp) inhibitor, quercetin (QU), into cancer cells and controlling their intracellular release extremely decreased the anticancer effects in multidrug resistant (MDR) tumors. To ove...

Descripción completa

Detalles Bibliográficos
Autores principales:	Guo, Yufan, Liu, Shuo, Luo, Fazhen, Tang, Dongyun, Yang, Tianshu, Yang, Xiuru, Xie, Yan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8878749/ https://www.ncbi.nlm.nih.gov/pubmed/35214154 http://dx.doi.org/10.3390/pharmaceutics14020422

Ejemplares similares

Intracellular codelivery of anti-inflammatory drug and anti-miR 155 to treat inflammatory disease
por: Teng, Chao, et al.
Publicado: (2020)

Microemulsion-based synergistic dual-drug codelivery system for enhanced apoptosis of tumor cells
por: Qu, Ding, et al.
Publicado: (2015)

Nucleus-selective codelivery of proteins and drugs for synergistic antitumor therapy
por: Yang, Lan, et al.
Publicado: (2022)

Codelivery of Phytochemicals with Conventional Anticancer Drugs in Form of Nanocarriers
por: Kumar, Girish, et al.
Publicado: (2023)

Self‐Stabilized Hyaluronate Nanogel for Intracellular Codelivery of Doxorubicin and Cisplatin to Osteosarcoma
por: Zhang, Yi, et al.
Publicado: (2018)

Self‐Stabilized Hyaluronate Nanogel for Intracellular Codelivery of Doxorubicin and Cisplatin to Osteosarcoma
por: Zhang, Yi, et al.
Publicado: (2018)

Nanosizing of drugs: Effect on dissolution rate
por: Dizaj, S. Maleki, et al.
Publicado: (2015)

Dual Stimuli-Triggered Nanogels in Response to Temperature and pH Changes for Controlled Drug Release
por: Kim, Yun Kyoung, et al.
Publicado: (2019)

Nanosized Drug Delivery Systems to Fight Tuberculosis
por: Bourguignon, Tom, et al.
Publicado: (2023)

Nanosized drug delivery strategies in osteosarcoma chemotherapy
por: Chen, Chenglong, et al.
Publicado: (2023)

Synthesis of stimuli-responsive nanosized ring-like colloids and cyclic polymers via a dual-template approach
por: Peng, Jinlei, et al.
Publicado: (2019)

Dual-modified liposome codelivery of doxorubicin and vincristine improve targeting and therapeutic efficacy of glioma
por: Zhang, Yue, et al.
Publicado: (2017)

IAEA Contribution to Nanosized Targeted Radiopharmaceuticals for Drug Delivery
por: Jalilian, Amir R., et al.
Publicado: (2022)

Preparation of Nanosized Pharmaceutical Formulations by Dual Centrifugation
por: Koehler, Jonas K., et al.
Publicado: (2023)

Recent advances in nanosized metal organic frameworks for drug delivery and tumor therapy
por: Yang, Junlei, et al.
Publicado: (2021)

Cancer Drug Delivery: Considerations in the Rational Design of Nanosized Bioconjugates
por: Kobayashi, Hisataka, et al.
Publicado: (2014)

Nanosized Drug Delivery Systems in Gastrointestinal Targeting: Interactions with Microbiota
por: Karavolos, Michail, et al.
Publicado: (2016)

Dual Targeted Nanoparticles for the Codelivery of Doxorubicin and siRNA Cocktails to Overcome Ovarian Cancer Stem Cells
por: Chen, Li, et al.
Publicado: (2023)

Development of Dual Drug Loaded Nanosized Liposomal Formulation by A Reengineered Ethanolic Injection Method and Its Pre-Clinical Pharmacokinetic Studies
por: Sarfraz, Muhammad, et al.
Publicado: (2018)

Targeting Intracellular Mycobacteria Using Nanosized Niosomes Loaded with Antibacterial Agents
por: Slavin, Yael Nicole, et al.
Publicado: (2021)

Biocompatible PEO-b-PCL Nanosized Micelles as Drug Carriers: Structure and Drug–Polymer Interactions
por: Chroni, Angeliki, et al.
Publicado: (2020)

Nanosized Drug Delivery Systems for Breast Cancer Stem Cell Targeting
por: Lv, Li, et al.
Publicado: (2021)

Micro- and Nanosized Carriers for Nose-to-Brain Drug Delivery in Neurodegenerative Disorders
por: Boyuklieva, Radka, et al.
Publicado: (2022)

Novel oral dosage regimen based on self-nanoemulsifying drug delivery systems for codelivery of phytochemicals – Curcumin and thymoquinone
por: Alwadei, Majed, et al.
Publicado: (2019)

Self-Assembling pH-Responsive Nanoparticle Platform Based on Pectin–Doxorubicin Conjugates for Codelivery of Anticancer Drugs
por: Tao, Yinghua, et al.
Publicado: (2021)

Progress in Nanocarriers Codelivery System to Enhance the Anticancer Effect of Photodynamic Therapy
por: Yang, Yu-Ling, et al.
Publicado: (2021)

Dual-Functional Peptide Driven Liposome Codelivery System for Efficient Treatment of Doxorubicin-Resistant Breast Cancer
por: Ahmed, Kamel S, et al.
Publicado: (2021)

Enhancement of solubility of poorly water soluble anti hypertensive drug by nanosizing approach
por: Thakar, Divyesh, et al.
Publicado: (2012)

Editorial: Nanosized Drug Delivery Systems: Colloids and Gels for Site Specific Targeting
por: Ehrbar, Martin, et al.
Publicado: (2020)

Integrating Therapeutic Ultrasound With Nanosized Drug Delivery Systems in the Battle Against Cancer
por: Moradi Kashkooli, et al.
Publicado: (2023)

Composing On-Program Triggers and On-Demand Stimuli into Biosensor Drug Carriers in Drug Delivery Systems for Programmable Arthritis Therapy
por: Lim, Yan Yik, et al.
Publicado: (2022)

Codelivery of Anticancer Drug and Photosensitizer by PEGylated Graphene Oxide and Cell Penetrating Peptide Enhanced Tumor-Suppressing Effect on Osteosarcoma
por: Zhang, Yi-Fei, et al.
Publicado: (2021)

Dual-Layered Nanogel-Coated Hollow Lipid/Polypeptide Conjugate Assemblies for Potential pH-Triggered Intracellular Drug Release
por: Chiang, Wen-Hsuan, et al.
Publicado: (2014)

Polysaccharide-Based Micro- and Nanosized Drug Delivery Systems for Potential Application in the Pediatric Dentistry
por: Katsarov, Plamen, et al.
Publicado: (2021)

A nanosized anionic MOF with rich thiadiazole groups for controlled oral drug delivery
por: Jiang, Ke, et al.
Publicado: (2021)

Dual Stimuli-Responsive Block Copolymers for Controlled Release Triggered by Upconversion Luminescence or Temperature Variation
por: Chung, Yueh-Chi, et al.
Publicado: (2019)

Recent Applications of Dual-Stimuli Responsive Chitosan Hydrogel Nanocomposites as Drug Delivery Tools
por: McCarthy, Pumtiwitt C., et al.
Publicado: (2021)

Self-assembled mPEG–PCL-g–PEI micelles for simultaneous codelivery of chemotherapeutic drugs and DNA: synthesis and characterization in vitro
por: Shi, Shuai, et al.
Publicado: (2012)

Codelivery of CRISPR-Cas9 and chlorin e6 for spatially controlled tumor-specific gene editing with synergistic drug effects
por: Deng, Shaohui, et al.
Publicado: (2020)

Codelivery of a cytotoxin and photosensitiser via a liposomal nanocarrier: a novel strategy for light-triggered cytosolic release
por: Yaghini, Elnaz, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_h4hpigqu18t94irh71tofvg6ga