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Ultrasound-Responsive Nrf2-Targeting siRNA-Loaded Nanobubbles for Enhancing the Treatment of Melanoma

The siRNA-mediated inhibition of nuclear factor E2-related factor 2 (Nrf2) can be an attractive approach to overcome chemoresistance in various malignant tumors, including melanoma. This work aims at designing a new type of chitosan-shelled nanobubble for the delivery of siRNA against Nrf2 in combin...

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Detalles Bibliográficos
Autores principales: Argenziano, Monica, Bessone, Federica, Dianzani, Chiara, Cucci, Marie Angèle, Grattarola, Margherita, Pizzimenti, Stefania, Cavalli, Roberta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8878772/
https://www.ncbi.nlm.nih.gov/pubmed/35214073
http://dx.doi.org/10.3390/pharmaceutics14020341