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Ultrasound-Responsive Nrf2-Targeting siRNA-Loaded Nanobubbles for Enhancing the Treatment of Melanoma
The siRNA-mediated inhibition of nuclear factor E2-related factor 2 (Nrf2) can be an attractive approach to overcome chemoresistance in various malignant tumors, including melanoma. This work aims at designing a new type of chitosan-shelled nanobubble for the delivery of siRNA against Nrf2 in combin...
Autores principales: | Argenziano, Monica, Bessone, Federica, Dianzani, Chiara, Cucci, Marie Angèle, Grattarola, Margherita, Pizzimenti, Stefania, Cavalli, Roberta |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8878772/ https://www.ncbi.nlm.nih.gov/pubmed/35214073 http://dx.doi.org/10.3390/pharmaceutics14020341 |
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