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Association of Tim-3/Gal-9 Axis with NLRC4 Inflammasome in Glioma Malignancy: Tim-3/Gal-9 Induce the NLRC4 Inflammasome

Tim-3/Gal-9 and the NLRC4 inflammasome contribute to glioma progression. However, the underlying mechanisms involved are unclear. Here, we observed that Tim-3/Gal-9 expression increased with glioma malignancy and found that Tim-3/Gal-9 regulate NLRC4 inflammasome formation and activation. Tim-3/Gal-...

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Detalles Bibliográficos
Autores principales: Sim, JeongMin, Park, JeongMan, Kim, Suwan, Hwang, Sojung, Sung, KyoungSu, Lee, Jung-Eun, Yang, SeungHo, Cho, Kyunggi, Lee, SungHwan, Moon, Jong-Seok, Ahn, JuWon, Lim, Jaejoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8878774/
https://www.ncbi.nlm.nih.gov/pubmed/35216164
http://dx.doi.org/10.3390/ijms23042028