The Role of Sirtuin 1 in Palmitic Acid-Induced Endoplasmic Reticulum Stress in Cardiac Myoblasts

Background: Lipotoxicity causes endoplasmic reticulum (ER) stress, leading to cell apoptosis. Sirtuin 1 (Sirt1) regulates gene transcription and cellular metabolism. In this study, we investigated the role of Sirt1 in palmitate-induced ER stress. Methods: Both H9c2 myoblasts and heart-specific Sirt1...

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Detalles Bibliográficos
Autores principales: Yang, Hsiang-Yu, Chen, Jhao-Ying, Huo, Yen-Nien, Yu, Pei-Ling, Lin, Pei-Zhen, Hsu, Shih-Che, Huang, Shih-Ming, Tsai, Chien-Sung, Lin, Chih-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8878829/
https://www.ncbi.nlm.nih.gov/pubmed/35207470
http://dx.doi.org/10.3390/life12020182

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8878829/
https://www.ncbi.nlm.nih.gov/pubmed/35207470
http://dx.doi.org/10.3390/life12020182

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