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The Role of Sirtuin 1 in Palmitic Acid-Induced Endoplasmic Reticulum Stress in Cardiac Myoblasts

Background: Lipotoxicity causes endoplasmic reticulum (ER) stress, leading to cell apoptosis. Sirtuin 1 (Sirt1) regulates gene transcription and cellular metabolism. In this study, we investigated the role of Sirt1 in palmitate-induced ER stress. Methods: Both H9c2 myoblasts and heart-specific Sirt1...

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Detalles Bibliográficos
Autores principales:	Yang, Hsiang-Yu, Chen, Jhao-Ying, Huo, Yen-Nien, Yu, Pei-Ling, Lin, Pei-Zhen, Hsu, Shih-Che, Huang, Shih-Ming, Tsai, Chien-Sung, Lin, Chih-Yuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8878829/ https://www.ncbi.nlm.nih.gov/pubmed/35207470 http://dx.doi.org/10.3390/life12020182

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