The Role of Intra-Patient Variability of Tacrolimus Drug Concentrations in Solid Organ Transplantation: A Focus on Liver, Heart, Lung and Pancreas

Tacrolimus, the keystone immunosuppressive drug administered after solid organ transplantation, presents a narrow therapeutic index and wide inter- and intra-patient pharmacokinetic variability (IPV). The latter has been fairly studied in kidney transplantation, where it could impact outcomes. Howev...

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Detalles Bibliográficos
Autores principales: Coste, Gwendal, Lemaitre, Florian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8878862/
https://www.ncbi.nlm.nih.gov/pubmed/35214111
http://dx.doi.org/10.3390/pharmaceutics14020379

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8878862/
https://www.ncbi.nlm.nih.gov/pubmed/35214111
http://dx.doi.org/10.3390/pharmaceutics14020379

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