Botulinum Neurotoxin Chimeras Suppress Stimulation by Capsaicin of Rat Trigeminal Sensory Neurons In Vivo and In Vitro

Chimeras of botulinum neurotoxin (BoNT) serotype A (/A) combined with /E protease might possess improved analgesic properties relative to either parent, due to inheriting the sensory neurotropism of the former with more extensive disabling of SNAP-25 from the latter. Hence, fusions of /E protease li...

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Detalles Bibliográficos
Autores principales: Antoniazzi, Caren, Belinskaia, Mariia, Zurawski, Tomas, Kaza, Seshu Kumar, Dolly, J. Oliver, Lawrence, Gary W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8878885/
https://www.ncbi.nlm.nih.gov/pubmed/35202143
http://dx.doi.org/10.3390/toxins14020116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8878885/
https://www.ncbi.nlm.nih.gov/pubmed/35202143
http://dx.doi.org/10.3390/toxins14020116

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