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A Unique Core–Shell Structured, Glycol Chitosan-Based Nanoparticle Achieves Cancer-Selective Gene Delivery with Reduced Off-Target Effects

The inherent instability of nucleic acids within serum and the tumor microenvironment necessitates a suitable vehicle for non-viral gene delivery to malignant lesions. A specificity-conferring mechanism is also often needed to mitigate off-target toxicity. In the present study, we report a stable an...

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Detalles Bibliográficos
Autores principales:	Cheng, Bei, Ahn, Hye-Hyun, Nam, Hwanhee, Jiang, Zirui, Gao, Feng J., Minn, Il, Pomper, Martin G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8878887/ https://www.ncbi.nlm.nih.gov/pubmed/35214105 http://dx.doi.org/10.3390/pharmaceutics14020373

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