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Discovery of SARS-CoV-2 3CL(Pro) Peptidomimetic Inhibitors through the Catalytic Dyad Histidine-Specific Protein–Ligand Interactions

As the etiological agent for the coronavirus disease 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) challenges the ongoing efforts of vaccine development and drug design. Due to the accumulating cases of breakthrough infections, there are urgent needs for broad-spectrum antiviral...

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Detalles Bibliográficos
Autores principales: Wang, Yaxin, Xu, Binghong, Ma, Sen, Wang, Hao, Shang, Luqing, Zhu, Cheng, Ye, Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8878928/
https://www.ncbi.nlm.nih.gov/pubmed/35216507
http://dx.doi.org/10.3390/ijms23042392