Cargando…
Discovery of SARS-CoV-2 3CL(Pro) Peptidomimetic Inhibitors through the Catalytic Dyad Histidine-Specific Protein–Ligand Interactions
As the etiological agent for the coronavirus disease 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) challenges the ongoing efforts of vaccine development and drug design. Due to the accumulating cases of breakthrough infections, there are urgent needs for broad-spectrum antiviral...
Autores principales: | Wang, Yaxin, Xu, Binghong, Ma, Sen, Wang, Hao, Shang, Luqing, Zhu, Cheng, Ye, Sheng |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8878928/ https://www.ncbi.nlm.nih.gov/pubmed/35216507 http://dx.doi.org/10.3390/ijms23042392 |
Ejemplares similares
-
4-Iminooxazolidin-2-One as a Bioisostere of Cyanohydrin Suppresses EV71 Proliferation by Targeting 3C(pro)
por: Xu, Binghong, et al.
Publicado: (2021) -
Conformationally Constrained Histidines in the Design of Peptidomimetics: Strategies for the χ-Space Control
por: Stefanucci, Azzurra, et al.
Publicado: (2011) -
Design, synthesis and biological evaluation of peptidomimetic benzothiazolyl ketones as 3CL(pro) inhibitors against SARS-CoV-2
por: Yang, Hanxi, et al.
Publicado: (2023) -
Human defensin-inspired discovery of peptidomimetic antibiotics
por: Luo, Gan, et al.
Publicado: (2022) -
The structure-based design of peptidomimetic inhibitors against SARS-CoV-2 3C like protease as Potent anti-viral drug candidate
por: Wang, Hao, et al.
Publicado: (2022)