Identification of a Quinone Derivative as a YAP/TEAD Activity Modulator from a Repurposing Library

The transcriptional regulators YAP (Yes-associated protein) and TAZ (transcriptional co-activator with PDZ-binding motif) are the major downstream effectors in the Hippo pathway and are involved in cancer progression through modulation of the activity of TEAD (transcriptional enhanced associate doma...

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Detalles Bibliográficos
Autores principales: Lauriola, Angela, Uliassi, Elisa, Santucci, Matteo, Bolognesi, Maria Laura, Mor, Marco, Scalvini, Laura, Elisi, Gian Marco, Gozzi, Gaia, Tagliazucchi, Lorenzo, Marverti, Gaetano, Ferrari, Stefania, Losi, Lorena, D’Arca, Domenico, Costi, Maria Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8878929/
https://www.ncbi.nlm.nih.gov/pubmed/35214125
http://dx.doi.org/10.3390/pharmaceutics14020391

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8878929/
https://www.ncbi.nlm.nih.gov/pubmed/35214125
http://dx.doi.org/10.3390/pharmaceutics14020391

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