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Mitochondrial Toxicity Associated with Imatinib and Sorafenib in Isolated Rat Heart Fibers and the Cardiomyoblast H9c2 Cell Line

Tyrosine kinase inhibitors (TKIs) are associated with cardiac toxicity, which may be caused by mitochondrial toxicity. The underlying mechanisms are currently unclear and require further investigation. In the present study, we aimed to investigate in more detail the role of the enzyme complexes of t...

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Detalles Bibliográficos
Autores principales: Bouitbir, Jamal, Panajatovic, Miljenko V., Krähenbühl, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8878993/
https://www.ncbi.nlm.nih.gov/pubmed/35216404
http://dx.doi.org/10.3390/ijms23042282