DNA Methylation Mediates EMT Gene Expression in Human Pancreatic Ductal Adenocarcinoma Cell Lines

Due to abundant stroma and extracellular matrix, accompanied by lack of vascularization, pancreatic ductal adenocarcinoma (PDAC) is characterized by severe hypoxia. Epigenetic regulation is likely one of the mechanisms driving hypoxia-induced epithelial-to-mesenchymal transition (EMT), responsible f...

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Detalles Bibliográficos
Autores principales: Urbanova, Maria, Buocikova, Verona, Trnkova, Lenka, Strapcova, Sabina, Kajabova, Viera Horvathova, Melian, Emma Barreto, Novisedlakova, Maria, Tomas, Miroslav, Dubovan, Peter, Earl, Julie, Bizik, Jozef, Svastova, Eliska, Ciernikova, Sona, Smolkova, Bozena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8879087/
https://www.ncbi.nlm.nih.gov/pubmed/35216235
http://dx.doi.org/10.3390/ijms23042117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8879087/
https://www.ncbi.nlm.nih.gov/pubmed/35216235
http://dx.doi.org/10.3390/ijms23042117

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