A(3) Adenosine Receptor Antagonists with Nucleoside Structures and Their Anticancer Activity

The overexpression of the A(3) adenosine receptor (AR) in a number of cancer cell types makes it an attractive target for tumor diagnosis and therapy. Hence, in the search for new A(3)AR ligands, a series of novel 2,N(6)-disubstituted adenosines (Ados) was synthesized and tested in radioligand bindi...

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Detalles Bibliográficos
Autores principales: Spinaci, Andrea, Buccioni, Michela, Dal Ben, Diego, Maggi, Federica, Marucci, Gabriella, Francucci, Beatrice, Santoni, Giorgio, Lambertucci, Catia, Volpini, Rosaria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8879107/
https://www.ncbi.nlm.nih.gov/pubmed/35215276
http://dx.doi.org/10.3390/ph15020164