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DNA Methylation and Detoxification in the Earthworm Lumbricus terrestris Exposed to Cadmium and the DNA Demethylation Agent 5-aza-2′-deoxycytidine

Earthworms are well-established model organisms for testing the effects of heavy metal pollution. How DNA methylation affects cadmium (Cd) detoxification processes such as the expression of metallothionein 2 (MT2), however, is largely unknown. We therefore exposed Lumbricus terrestris to 200 mg conc...

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Detalles Bibliográficos
Autores principales: Aigner, Gerhard P., Nenning, Pamela, Fiechtner, Birgit, Šrut, Maja, Höckner, Martina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8879108/
https://www.ncbi.nlm.nih.gov/pubmed/35202286
http://dx.doi.org/10.3390/toxics10020100