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Design, Synthesis, and Biological Evaluation of 4,4’-Difluorobenzhydrol Carbamates as Selective M(1) Antagonists

Due to their important role in mediating a broad range of physiological functions, muscarinic acetylcholine receptors (mAChRs) have been a promising target for therapeutic and diagnostic applications alike; however, the list of truly subtype-selective ligands is scarce. Within this work, we have ide...

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Detalles Bibliográficos
Autores principales: Kilian, Jonas, Ozenil, Marius, Millard, Marlon, Fürtös, Dorka, Maisetschläger, Verena, Holzer, Wolfgang, Wadsak, Wolfgang, Hacker, Marcus, Langer, Thierry, Pichler, Verena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8879200/
https://www.ncbi.nlm.nih.gov/pubmed/35215360
http://dx.doi.org/10.3390/ph15020248